What Is Granuloma

The word "granuloma" originates from the Latin word "granum," meaning "grain" or "seed." Granulomas  appear as small lumps with a distinctive cellular make-up that can be observed by using a microscope. They can develop on almost any internal or external body part. There are numerous diverse granulomatous diseases, including Crohn's disease, tuberculosis and sarcoidosis.

The cells that form a granuloma come from the immune system, which is the body's defence against disease and illness. Its key component parts are macrophages and leukocytes, cells that originate in the bone marrow and pass along the lymphatic vessels to various parts of the body.

Macrophages are cells that attack alien germs and bacteria by surrounding and engulfing them. Macrophages exude various biochemicals that influence the action of the surrounding cells. For example, cytokines are one type of biochemical that may be secreted, which causes inflammation, the reason behind an infected area becoming inflamed.

Lymphocytes are smaller immune cells that lay dormant until triggered by meeting a foreign body, an antigen, and then begin to secrete antibodies to fight the invader. The most common types of lymphocytes are T cells and B cells, and the antibodies they produce are called immunoglobulins. When foreign bodies such as bacteria, viruses, and toxins resist the action of macrophages, the resisting particles are attacked by the macrophages, leading to the formation of a granuloma, a cluster of a variety of cells forming a distinct nodule.

Sarcoidosis is a disease of unknown origin that is distinguishable by the formation of granulomas in various organs. It is the development of these granulomas and the ensuing tissue damage that cause sarcoidosis symptoms. However, in a lot of instances , granulomas do not form in key areas of the body or appear in such significant numbers that they lead to symptoms. The manifestation of the disease can differ greatly between sufferers. Some patients experience a short lived, mild attack, whereas in others the disease becomes chronic and incapacitating.

Typical sarcoidosis treatment is the prescribing of corticosteroids, anti-inflammatory drugs, but prolonged use can lead to unwanted and potentially dangerous side-effects. However, an all natural sarcoidosis alternative treatment is an option that is available.

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